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Volume 6 - Number 29 | July 17, 2008

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In This Week's Issue

Bio-Reference Laboratories’ GeneDx to Launch Genetic Test Based on Illumina GA This Fall

New Base Caller Improves Accuracy of Long Illumina Reads; May Allow De Novo Assembly

Tim Hubbard On Sequence Databases, Ensembl, ENCODE, and More

Sequencing-Related Papers of Note, June 2008

Illumina, Avantome, Roche, 454 Life Sciences, Applied Biosystems, InteRNA Genomics, Biotique Systems, Genomatix Software, BioTeam, Invitrogen, Active Motif, Genetic Technologies, LabCorp, 23andMe, Oxford Biomedical Research Centre, International Genomics Consortium, LabVantage, NHGRI, US Department of Agriculture, NIH, US Genomics

SOLiD Software Analysis Tools, GenomeQuest 5.0, Metagenomic DNA Isolation Kit

Steven Pinker, Stephen Pentoney, Joseph Hogan

Features
Quark Taps Glaucoma Drug to Be Its First Novel RNAi Agent, CEO Speaks Out on Silence
Quark’s investigational glaucoma treatment would be its first completely proprietary siRNA drug, which is expected to help the company avoid the kind of confusion it said has plagued its other clinical candidates, which incorporate chemical structures licensed from other firms.

Opko, Frost Group Ask Court to Dismiss Conspiracy Charges in Suit Filed by Rival
Opko, responding to a lawsuit by rival Ophthalmic Imaging Systems charging it with conspiring with a former employee to interfere with OIS’ business activities, told the judge that the activities were part of standard business practices. It also said OIS’ case is weak because it “relies on secondary theories of liability.”

With Phase I SBIR Grant, AM Biotechnologies Looks to Apply Thioaptamer Tech to siRNAs
The $199,999 award from the National Institute of General Medical Sciences will help the company develop its core thioaptamer technology for synthesizing modified RNA oligonucleotides, including siRNAs.

IP Update
USPTO Publishes One Patent, Two Patent Applications Related to RNAi


Strands
Novartis, Alnylam Pharmaceuticals, Dicerna Pharmaceuticals, Silence Therapeutics


People in the News
Vin Miles, Jeff Vick, Iain Ross, Jeremy Curnock Cook



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